>>>Кто нибудь знает механизм рассылки подобной дряни? Как заставить sendmail не принимать 
>>>письма с несуществующим адресом в поле TО заголовка? 
>>
>>И будут приходить ( RFC2505 ), пока не будете проверять "легетивность" sender'а. 
>>
>
>Спасибо, идея понятна. Можете подсказать, как это сделать? E-mail основана на DNS именах.
Легитимность sender'а определяется наличием соответствием имена хоста в
прямой и обратной зоне DNS.
RFC 1033                                                               
There should be one A record for each address of a host.               
PTR's should use official names and not aliases.                       
                                                                       
To add a new host to your zone files:                                  
 Edit the appropriate zone file for the domain the host is in.         
 Add an entry for each address of the host.                            
 Optionally add CNAME, HINFO, WKS, and MX records.                     
 Add the reverse IN-ADDR entry for each host address in the appropriate
 zone files for each network the host in on.                           
RFC 1123                                                                
A canonicalized name either identifies a host directly or is an MX name;
it cannot be a CNAME.                                                   
                                                                        
RFC 2181                                                                
10.2. PTR records                                                       
  Confusion about canonical names has lead to a belief that a PTR       
  record should have exactly one RR in its RRSet.  This is incorrect,   
  the relevant section of RFC1034 (section 3.6.2) indicates that the    
  value of a PTR record should be a canonical name.  That is, it should 
  not be an alias.  There is no implication in that section that only   
  one PTR record is permitted for a name.  No such restriction should   
  be inferred.                                                          
  Note that while the value of a PTR record must not be an alias, there 
  is no requirement that the process of resolving a PTR record not      
  encounter any aliases.  The label that is being looked up for a PTR   
  value might have a CNAME record.  That is, it might be an alias.  The 
  value of that CNAME RR, if not another alias, which it should not be, 
  will give the location where the PTR record is found.  That record    
  gives the result of the PTR type lookup.  This final result, the      
  value of the PTR RR, is the label which must not be an alias.         
10.3. MX and NS records                                                 
  The domain name used as the value of a NS resource record, or part of 
  the value of a MX resource record must not be an alias.               
RFC2821:                                                                                                                          
4.3.1                                                                   
[..]                                                                    
   Note: all the greeting-type replies have the official name (the      
   fully-qualified primary domain name) of the server host as the first 
   word following the reply code.  Sometimes the host will have no      
   meaningful name.  See 4.1.3 for a discussion of alternatives in these
   situations.                                                          
[...]                                                                   
RFC1035:                                                                   
3.5. IN-ADDR.ARPA domain                                                   
The Internet uses a special domain to support gateway location and         
Internet address to host mapping.                                          
The intent of this domain is to provide a guaranteed method to perform     
host address to host name mapping,                                         
and to facilitate queries to locate all gateways on a particular network   
in the Internet.                                                           
                                                                           
Note that both of these services are similar to functions that could be    
performed by inverse queries; the difference is                            
that this part of the domain name space is structured according to address,
and hence can guarantee that the appropriate data can be located without   
an exhaustive search of the domain space.                                  
                                                                           
Address nodes are used to hold pointers to primary host names              
in the normal domain space.                                                
Еще может быть запись в реверсной зоне, что хост 
является SMTP релеем (MTAMARK _perm._smtp._srv.$4.$3.$2.$1.in-addr.arpa.), 
Неплохо бы проверить наличее ящика из MAIL FROM: <...>  через 
MX прямой зоны, выполнив callback.
Вам надо смотреть софт типа 
http://www.snertsoft.com/sendmail/milter-sender/
http://www.milter.info/ 
К Сергею Вакуленко можно заглянуть
http://www.vak.ru/doku.php/proj/sendmail/antispam
Плюс фильтры типа SpamAssassin.